NIPER, GUWAHATI conducts research in different areas of pharmaceutical sciences keeping in view the national and local needs.
Molecular genomics and expression of various targets in Ischemia Stroke disorder etc.
Pharmacogenomics study in Diabetes, use of drugs like clopidogrel and its pharmacogenomic approaches.
Investigation in Molecular pathophysiology of various targets in Neuropathic pain and its future treatment.
Study in the field of Proteomics to develop various target drugs for therapeutic approaches.
Development of synthetic riboswitches to suppress gene expression in case of various life-threatening diseases.
Development of deoxyribozymes, which can degrade RNA of various oncogenes. Generation of various novel protein coding sequences, which can be further developed as biopharmaceuticals.
Suitability of G-quadruplexes as gene regulation tool in cancer and other diseases.
Directed evolution of therapeutic proteins for enhanced activity and least immunogenicity.
Study in the field of Molecular Hematology to observe the molecular details in various diseases like Multiple Myeloma, Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Myodisplastic syndrome.
Protective effect of Carissa carandas against cyclophosphamide-induced toxicity.
Evaluate the effect of Naringenin and Crocetin on cyclophosphamide-induced testicular toxicity.
Studies on anti-tumor activity of various plants available in the North East region Effect of Ocimum sanctum in experimental diabetic neuropathy.
Anti-inflammatory activity of Morabulus jalepa in acute and chronic models of inflammation in rats.
Effect of Green tea polyphenols on the pharmacokinetics of Paclitaxel
Evaluate anti-inflammatory activity of Hibiscus rosa sinensis in rats.
Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice.
Studies on Neurodegenerative diseases like Parkinson’s, Alzheimer’s etc.
Pharmacological studies of various anti cancer agents and plant extracts.
Pharmacological studies in depression.
Adverse Drug Reaction (ADR) monitoring
Drug Drug Interaction (DDI) studies
ADR monitoring of Anti-TB therapy
Analytical and bioanalytical method development and validation
Pharmacokinetic studies of drugs and metabolites
Identification and characterization of impurities in drug substances
Forced degradation studies and characterization of degradation products
Short-term/accelerated, mid-term and long-term stability testing of formulations
Pre-formulation (physicochemical parameters & excipient compatibility) studies
Chemical characterization of biomarkers in herbal products
Dosage form development and optimization for poorly water soluble drug molecules
Drug targeting using ligand anchored lipid-and polymer-based nanoarchitectonics
Micro-and nano-theragnosis concepts for the early detection and treatment of malignant diseases and other life-threatening diseases
Eradication of biofilm-producing microorganisms from the surfaces of implanted or inserted medical devices into human body
Pharmacoengineering, molecular pharmaceutics, biopharmaceutics & pharmacokinetics
Drug-in-adhesive matrix/reservoir type transdermal drug delivery systems
Organ & lymphatic delivery of nanomedicines along with deep molecular insights
Translational cutting-edge biomedical research and biomaterials fabrication.
|TITLE||PI/CO-PI||FUNDING AGENCY||APPROVED FUND||APPROVED YEAR|
|Himalayan Fellowship Proposal for NMHS Grant||PI - Dr. USN Murty
Co-PI - Dr. VGM Naidu
|Ministry of Environment & Forestry||127 Lakhs||2018|
|Systematic and Scientific investigation of selected medicinal plants from north eastern part of India for rheumatoid arthritis and derivation of mechanism of action using bioguided fractionation methods besides identification and characterization of lead molecules using liquid-liquid separation technique.||PI - Dr. USN Murty
Co-PI - Dr. VGM Naidu
|Gold Capsuled Combination Nanomedicine for Target Specic Therapy of Chemoresistant Breast Tumors.||Co-PI - Dr. VGM Naidu||DST-SERB||12.65 Lakhs||2017|
|Prophylactic transdermal patch against neurotoxin poisoning in biological warfare situations.||Co-PI - Dr. Subham Banerjee||BIRAC-SRISTI GYTI Award, Dept. of Biotechnology (DBT), Govt. of India||15 Lakhs||2017|
|DBT Twinning Collaborative Project between NIPER-Guwahati & IITR-Lucknow.||PI - Dr. Utpal Mohan||DBT||48.10 Lakhs||2017|
|DBT-BioCARE||PI - Dr. Shubhangi Kaushik||DBT||43 Lakhs||2017|
|Design and Fabrication of EphA2 receptor targeting lipid polymer hybrid particles for sensitising breast cancer stem cells to enhance efficiency of chemotherapy.||PI - Dr. VGM Naidu||DST-SERB||11.10 Lakhs||2015|
|DBT Twinning Collaborative Project between NIPER-Guwahati & NIPER- Hyderabad.||PI - Dr. Ranadeep Gogoi||DBT||50.70 Lakhs||2014|
|DST-WOS-A Project||PI - Dr. Swapnil Sinha
Mentor - Dr. Utpal Mohan