Research

Publications at NIPER Guwahati


2019

Kuldeep Mahato, Sahil Nagpal, Mahero Ayesha Shah, Ananya Srivastava, Pawan Kumar Maurya, Shounak Roy, Amit Jaiswal, Renu Singh, Pranjal Chandra. Gold nanoparticle surface engineering strategies and their applications in biomedicine and diagnostics. 3 Biotech (2019) 9: 57.

Ashutosh Kumar, Buddhadev Purohit, Kuldeep Mahato, Riddhipratim Mandal, Ananya Srivastava, Pranjal Chandra. Gold-Iron Bimetallic Nanoparticles Impregnated reduced Graphene Oxide based Nanosensor for Label-Free Detection of Biomarker related to Non-Alcoholic fatty Liver Disease. Electroanalysis, In Press. 2019.

Dimple Chouhan, Namit Dey, Nandana Bhardwaj, Biman B. Mandal, Emerging and innovative approaches for wound healing and skin regeneration: Current status and advances. Biomaterials 216 (2019) 119267.

Puri, D., Khatik, G.L., Tamilvanan, S. Studies on olive-and silicone-oils-based Janus macroemulsions containing ginger to manage primary dysmenorrheal pain. (2019) Materials Science and Engineering C, 100, pp. 276-285.

Pramod Kumar, Gajanand Sharma, Varun Gupta, Ramanpreet Kaur, Kanika Thakur, Ruchi Malik, Anil Kumar, Naveen Kaushal, Om Prakash Katare, Kaisar Raza. 2019. Oral Delivery of Methylthioadenosine to the Brain Employing Solid Lipid Nanoparticles: Pharmacokinetic, Behavioral, and Histopathological Evidences. AAPS PharmSciTech. 20,74. https://doi.org/10.1208/s12249-019-1296-0.

Subham Banerjee, Subhadeep Roy, Kaushik Nath Bhaumik, Jonathan Pillai. Mechanisms of the effectiveness of lipid nanoparticle formulations loaded with anti-tubercular drugs combinations toward overcoming drug bioavailability in tuberculosis. Journal of Drug Targeting. In Press 2019.

Piyali Dey, Subham Banerjee, Santa Mandal, Pronobesh Chattopadhyay. Design and Evaluation of Anti-fibrosis Drug Engineered Resealed Erythrocytes for Targeted Delivery. Drug Delivery and Translational Research, Accepted, 2019.

Koushik Dutta, Subham Banerjee, Pronobesh Chattopadhyay. Exploration of Mucuna pruriens (Linn) starch powder formulations as a natural non-lethal riot control agent. Toxicology and Environmental Health Sciences. In Press. 2019.

Subham Banerjee and Jonathan Pillai. Solid Lipid Matrix Mediated Nanoarchitectonics for Improved Oral Bioavailability of Drugs. Expert Opinion on Drug Metabolism & Toxicology. 15:499-515. 2019.

Ramu Adela, Podduturu Naveen Chander Reddy, Tarini Shankar Ghosh, Suruchi Aggarwal, Amit Kumar Yadav, Bhabatosh Das and Sanjay K. Banerjee Serum protein signature of coronary artery disease in type 2 diabetes mellitus. Journal of Translational Medicine201917:17

Lingesh A, Paul D, Naidu V, Satheeshkumar N. AMPK activating and Anti adipogenic potential of Hibiscus rosa sinensis flower in 3T3-L1 cells. J Ethnopharmacol. 2019 6;233:123-130

Sukhwinder Singh Sohal, Mathew Suji Eapen, Vegi G.M. Naidu, Pawan Sharma IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette. ERJ Open Research Feb 2019, 5 (1) 00159-2018.

Choubey, P., Kwatra, M., Pandey, S.N., Kumar, D., Dwivedi, D.K., Rajput, P., Mishra, A., Lahkar, M., Jangra, A. Ameliorative effect of fisetin against lipopolysaccharide and restraint stress-induced behavioral deficits via modulation of NF-κB and IDO-1 (2019) Psychopharmacology, 236 (2), pp. 741-752.

Guntuku, L., Gangasani, J.K., Thummuri, D., Borkar, R.M., Manavathi, B., Ragampeta, S., Vaidya, J.R., Sistla, R., Vegi, N.G.M. IITZ-01, a novel potent lysosomotropic autophagy inhibitor, has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo (2019) Oncogene, 38 (4), pp. 581-595.

Kakarla, S.G., Mopuri, R., Mutheneni, S.R., Bhimala, K.R., Kumaraswamy, S., Kadiri, M.R., Gouda, K.C., Upadhyayula, S.M. Temperature dependent transmission potential model for chikungunya in India (2019) Science of the Total Environment, 647, pp. 66-74.

Kakarla, S.G., Caminade, C., Mutheneni, S.R., Morse, A.P., Upadhyayula, S.M., Kadiri, M.R., Kumaraswamy, S. Lag effect of climatic variables on dengue burden in India (2019) Epidemiology and infection, 147, p. e170.


2018

Mohini Mishra, Pramod Kumar, Jitendra Singh Rajawat, Ruchi Malik, Gitanjali Sharma and Amit Modgil. 2018. Nanotechnology: Revolutionizing the Science of Drug Delivery. Current Pharmaceutical Design. DOI: 10.2174/1381612825666190206222415.

Riddhipratim Mandal, Anupriya Baranwal, Ananya Srivastava, Pranjal Chandra. Evolving trends in bio/chemical sensor fabrication incorporating bimetallic nanoparticles. Biosensors and Bioelectronics, Volume 117, 546-561, 2018.

Anupriya Baranwal, Ananya Srivastava, Pradeep Kumar, Vivek K. Bajpai, Pawan Kumar Maurya, Pranjal Chandra. Prospects of Nanostructured Materials as Antimicrobial Agents. Frontiers in Microbiology Volume 9, Article 422, Pages 1-10, 2018

Sachin Kadian, Brahm Dutt Arya, Sumit Kumar, Shailesh N. Sharma, Rishi Pal Chauhan, Ananya Srivastava, Pranjal Chandra, Surinder P. Singh. Synthesis and Application of PHT‐TiO2 Nanohybrid for Amperometric Glucose Detection in Human Saliva Sample. Electroanalysis, Volume30, Issue11 Pages 2793-2802, 2018.

Gundala, N.K.V., Naidu, V.G.M., Das, U.N. Amelioration of streptozotocin-induced type 2 diabetes mellitus in Wistar rats by arachidonic acid (2018) Biochemical and Biophysical Research Communications, 496 (1), pp. 105-113.

KV, A., Madhana, R.M., JS, I.C., Lahkar, M., Sinha, S., Naidu, V.G.M. Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice (2018) Behavioural Brain Research, 344, pp. 73-84.

Chouhan, D., Lohe, T.-U., Samudrala, P.K., Mandal, B.B. In Situ Forming Injectable Silk Fibroin Hydrogel Promotes Skin Regeneration in Full Thickness Burn Wounds (2018) Advanced Healthcare Materials, 7 (24), art. no. 1801092

Potnuri, A.G., Allakonda, L., Lahkar, M. Crocin attenuates cyclophosphamide induced testicular toxicity by preserving glutathione redox system (2018) Biomedicine and Pharmacotherapy, 101, pp. 174-180.

Dwivedi, D.K., Kumar, D., Kwatra, M., Pandey, S.N., Choubey, P., Lahkar, M., Jangra, A. Voluntary alcohol consumption exacerbated high fat diet-induced cognitive deficits by NF-κB-calpain dependent apoptotic cell death in rat hippocampus: Ameliorative effect of melatonin (2018) Biomedicine and Pharmacotherapy, 108, pp. 1393-1403.

Thummuri, D., Guntuku, L., Challa, V.S., Ramavat, R.N., Naidu, V.G.M. Abietic acid attenuates RANKL induced osteoclastogenesis and inflammation associated osteolysis by inhibiting the NF-KB and MAPK signaling (2018) Journal of Cellular Physiology, 234 (1), pp. 443-453.

Mousum, S.A., Ahmed, S., Gawali, B., Kwatra, M., Ahmed, A., Lahkar, M. Nyctanthes arbor-tristis leaf extract ameliorates hyperlipidemia- and hyperglycemia-associated nephrotoxicity by improving anti-oxidant and anti-inflammatory status in high-fat diet–streptozotocin-induced diabetic rats. (2018) Inflammopharmacology, 26 (6), pp. 1415-1428.

Saha, P., Johny, E., Dangi, A., Shinde, S., Brake, S., Eapen, M.S., Sohal, S.S., Naidu, V.G.M., Sharma, P. Impact of Maternal Air Pollution exposure on children's lung health: An Indian perspective (2018) Toxics, 6 (4), art. no. 68.

Baghel, D.S., Chopra, S., Bhatia, A., Tamilvanan, S. Amalgamation of ayurvedic concept with modern medical practice to manage kidney stone disease (urolithiasis): An abbreviated review (2018) Indian Drugs, 55 (11), pp. 7-18.

Jonnalagadda, V.G., Char, H.P., Samudrala, P.K. Re: Cohen et al.:Impact of Statin Intake on Kidney Stone Formation (Urology 2018) (2018) Urology, 118, p. 244.

Jonnalagadda, V.G., Char, H.P., Samudrala, P.K. Prediabetes, diabetes mellitus, and anti-diabetic treatment: Is anyone still healthy? (2018) Diabetes/Metabolism Research and Reviews, 34 (5), art. no. e3009

Mundhe, N., Kumar, P., Arora, I., Ahmed, S., Lahkar, M. Differential effect of NDGA on cisplatin-induced nephrotoxicity in Spargue-Dawley rats (2018) Immunopharmacology and Immunotoxicology, . Article in Press.

Tamilvanan, S., Chanda, P. Ornidazole-loaded polyethylene glycol-based micron-level particles: influence of eutectic liquid on reservoir-type particle formation, drug entrapment efficiency and drug dissolution or release behaviour (2018) Polymer Bulletin. Article in Press.

Saha, P.; Johny, E.; Dangi, A.; Shinde, S.; Brake, S.; Eapen, M.S.; Sohal, S.S.; Naidu, V.; Sharma, P. Impact of Maternal Air Pollution Exposure on Children’s Lung Health: An Indian Perspective. Toxics 2018, 6, 68.

Chouhan D, Lohe TU, Samudrala PK, Mandal BB. In Situ Forming Injectable Silk Fibroin Hydrogel Promotes Skin Regeneration in Full Thickness Burn Wounds. Adv Healthc Mater. 2018 Dec;7(24).

Yogendra Pratap Singh, Joseph Christakiran Moses, Nandana Bhardwaj and Biman B. Mandal. Injectable hydrogels: a new paradigm for osteochondral tissue engineering. J. Mater. Chem. B, 2018,6, 5499-5529

Subham Banerjee, Amit Kundu. Lipid-drug conjugates: a potential nanocarrier system for oral drug delivery applications. DARU Journal of Pharmaceutical Sciences. 26:209, 2018.

Pronobesh Chattopadhyay, Pallabi Paul, Subham Banerjee, Santa Mandal, Sanjeev Karmakar, Danswrang Goyary, Sunil Dhiman, Srijita Chakraborty, P. S. Raju, Sanjai K Dwivedi. Intranasal delivery of obidoxime and atropine biodegradable nanosphere: A new therapeutic and antidotal approach for quick response and rapid management of organophosphate poisoning. Drug Research. 68:1-12. 2018.

Kv, Athira; Madhana, Rajaram Mohanrao; Js, Indu Chandran; Lahkar, Mangala; Sinha, Swapnil; Naidu, V G M. Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. Behavioural brain research, 344, 73-84, 2018.

Dwivedi, D.K., Kumar, D., Kwatra, M., Pandey, S.N., Choubey, P., Lahkar, M., Jangra, A.Voluntary alcohol consumption exacerbated high fat diet-induced cognitive deficits by NF-κB-calpain dependent apoptotic cell death in rat hippocampus: Ameliorative effect of melatonin. Biomedicine and Pharmacotherapy, 108: 1393-1403, 2018.

Mousum, S.A., Ahmed, S., Gawali, B., Kwatra, M., Ahmed, A., Lahkar, M. Nyctanthes arbortristis leaf extract ameliorates hyperlipidemia- and hyperglycemia-associated nephrotoxicity by improving anti-oxidant and anti-inflammatory status in high-fat diet–streptozotocin-induced diabetic rats. Inflammopharmacology, 26, 1415-1428, 2018.

Choubey, P., Kwatra, M., Pandey, S.N., Kumar, D., Dwivedi, D.K., Rajput, P., Mishra, A., Lahkar, M., Jangra, A. Ameliorative effect of fisetin against lipopolysaccharide and restraint stress-induced behavioral deficits via modulation of NF-κB and IDO-1. Psychopharmacology, 2018. Article in Press.

Thummuri, D., Guntuku, L., Challa, V.S., Ramavat, R.N., Naidu, V.G.M. Abietic acid attenuates RANKL induced osteoclastogenesis and inflammation associated osteolysis by inhibiting the NF-KB and MAPK signalling. Journal of Cellular Physiology, 234, 443-453, 2018

Athira KV, Rajaram Mohanrao, Madhanaa Indu, Chandran JS, MangalaLahkara, SwapnilSinha, VGM Naidu, Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. Behavioural Brain Research. 2018; 344:73-84.

Potnuri AG, Allakonda L, Lahkar M. Crocin attenuates cyclophosphamide induced testicular toxicity by preserving glutathione redox system. Biomedicine & Pharmacotherapy. 2018; 101:174-180.

Dimple Chouhan, Tshewuzo‐u Lohe, Pavan Kumar Samudrala, Biman B Mandal. In Situ Forming Injectable Silk Fibroin Hydrogel Promotes Skin Regeneration in Full Thickness Burn Wounds. Advanced healthcare materials, 2018.

Pavan Kumar Samudrala, venu Gopal Jonnalagadda, Harish Prabhanna Char. Effect of Statins in Urolithiasis: One More Area to Explore? Urology, 2018

VG Jonnalagadda, HP Char, Pavan Kumar Samudrala. Prediabetes, diabetes mellitus, and anti‐diabetic treatment: Is anyone still healthy. Diabetes/Metabolism Research and Reviews, 2018


2017

Ajay Godwin Potnuri, Sundar Kumar Kondru, Pavan Kumar Samudrala, Lingesh Allakonda. Prevention of Adriamycin induced cardiotoxicity in rats — A comparative study with subacute angiotensin-converting enzyme inhibitor and nonselective beta blocker therapy. IJC Metaboloc & Endocrine 2017. 14:59-64.

Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy; P Komirishetty, A Areti, R Gogoi, R Sistla, A Kumar, Neuropharmacology, 2017, 113, 137-147.

Komirishetty P; Areti A; Gogoi R; Sistla R; Kumar A., Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy. Neuropharmacology. 2017; 113(Pt A):137-147.

Vadlapudi V; Borah N; Yellusani KR; Gade S; Reddy P; Rajamanikyam M; Vempati LNS; Gubbala SP; Chopra P; Upadhyayula SM; Amanchy R., Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus. Scientific Reports. 2017;7(1):7325

Kumar P; Barua CC; Sulakhiya K; Sharma RK., Curcumin Ameliorates Cisplatin-Induced Nephrotoxicity and Potentiates Its Anticancer Activity in SD Rats: Potential Role of Curcumin in Breast Cancer Chemotherapy. Frontiers in Pharmacology 2017; 8:132.

Kumar M; Dahiya V; Kasala ER; Bodduluru LN; Lahkar M., The renoprotective activity of hesperetin in cisplatin induced nephrotoxicity in rats: Molecular and biochemical evidence. Biomed. Pharmacotherapy 2017; 89:1207-1215.

Lihite RJ; Lahkar M; Das S; Hazarika D; Kotni M; Maqbool M; Phukanb S; Study on adverse drug reactions in a tertiary care hospital of Northeast India. Alexandria Journal of Medicine, 2017; 53 (2):151-156.

Borgohain P; Lahkar M; Ahmed S; Chowdhury L; Kumar S; Pant R.; Choubey A., Small Molecule Inhibiting Nuclear Factor-kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan-Induced Diabetic Nephropathy in Rat. Basic Clin. Pharmacol. Toxicol. 2017;120(5):442-449.

Pant R; Jangra A; Kwatra M; Singh T; Kushwah P; Bezbaruah BK; Gurjar SS; Phukan S., Cognitive deficits induced by combined exposure of stress and alcohol mediated through oxidative stress-PARP pathway in the hippocampus. Neurosci. Lett. 2017; 653:208-214.

Karnam KC; Ellutla M; Bodduluru LN; Kasala ER; Uppulapu SK; Kalyankumarraju M; Lahkar M., Preventive effect of berberine against DMBA-induced breast cancer in female Sprague Dawley rats. Biomed. Pharmacother. 2017; 92:207-214.

Kumar P; Sulakhiya K; Barua CC; Mundhe N., TNF-α, IL-6 and IL-10 expressions, responsible for disparity in action of curcumin against cisplatin-induced nephrotoxicity in rats. Mol. Cell Biochem. 2017; 431(1-2):113-122.

Rajamanikyam M; Vadlapudi V; Amanchy R; Murty USN., Endophytic Fungi as Novel Resources of natural Therapeutics. Braz. Arch. Biol. Technol. 2017; 60: e17160542.

Rajput P; Jangra A; Kwatra M; Mishra A; Lahkar M., Alcohol aggravates stress-induced cognitive deficits and hippocampal neurotoxicity: Protective effect of melatonin. Biomed. Pharmacother. 2017; 91: 457-466.

Borgohain M.P; Chowdhury L.; Ahmed S.; Bolshette N; Devasani K; Das T.J.; Mohapatra A;.Lahkar M., Renoprotective and antioxidative effects of methanolic Paederia foetida leaf extract on experimental diabetic nephropathy in rats. Journal of Ethnopharmacology 2017; 198, 451-459.

Gade S; Rajamanikyam M; Vadlapudi V; Nukala K.M.; Aluvala R; Giddigari C; Karanam NJ; Barua N.C.; Pandey R; Saradhi V; Upadhyayula V; Sripadi P; Amanchy R; Murty USN., Acetylcholinesterase inhibitory activity of stigmasterol & hexacosanol is responsible for larvicidal and repellent properties of Chromolaena odorata. Biochim. Biophys. Acta. 2017;1861(3):541-550.

Jangra A; Sriram CS; Dwivedi S; Gurjar SS; Hussain MI; Borah P; Lahkar M., Sodium Phenylbutyrate and Edaravone Abrogate Chronic Restraint Stress-Induced Behavioral Deficits:Implication of Oxido-Nitrosative, Endoplasmic Reticulum Stress Cascade, and Neuroinflammation. Cell. Mol. Neurobiol. 2017;37(1):65-81.

Bhilare K.D.; Banerjee U.C.; Mohan U., Template independent synthesis of nucleic acid libraries. Journal of DNA and RNA Research. 2017; 1(2), 1-9.

Pardeshi R; Bolshette N; Gadhave K; Ahire A; Ahmed S; Cassano T; Gupta VB; Lahkar M., Insulin signaling: An opportunistic target to minify the risk of Alzheimer’s disease. Psychoneuroendocrinology. 2017; 83:159-171.

Rajamanikyam M; Vadlapudi V; Parvathaneni SP; Koude D; Sripadi P; Misra S; Amanchy R; Upadhyayula SM., Isolation and characterization of phthalates from Brevibacterium mcbrellneri that cause cytotoxicity and cell cycle arrest. EXCLI J. 2017;16:375-387.

Potnuri AG, Kondru SK, Samudrala PK, Allakonda L. Prevention of Adriamycin induced cardiotoxicity in rats- A comparative study with subacute angiotensin-converting enzyme inhibitor and nonselective beta blocker therapy. IJC Metabolic & Endocrine. 2017;14:59-64.

Jeengar MK, Thummuri D, Magnusson M, Naidu VG, Uppugunduri S. Uridine Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice. Scientific Reports. 2017;7:3924.

Thummuri D, Naidu VG, Chaudhari P. Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-κB and MAPK signalling. Journal of Molecular Medicine. 2017;95(10):1065-76.

Rajamanikyam M, Gade S, Vadlapudi V, Parvathaneni SP, Koude D, Dommati AK, Tiwari AK, Misra S, Sripadi P, Amanchy R, Upadhyayula SM. Biophysical and biochemical characterization of active secondary metabolites from Aspergillus allahabadii. Process Biochemistry. 2017;56:45-56.


2016

Antioxidant and antitumor efficacy of Luteolin, a dietary flavone on benzo (a) pyrene-induced experimental lung carcinogenesis; ER Kasala, LN Bodduluru, CC Barua, R Gogoi, Biomedicine & Pharmacotherapy, 2016, 82, 568-577.

K. V. Athira, Rajaram Mohanrao Madhana, Eshvendar Reddy Kasala, Pavan Kumar Samudrala, Mangala Lahkar, and Ranadeep Gogoi. Morin Hydrate Mitigates Cisplatin-Induced Renal and Hepatic Injury by Impeding Oxidative/Nitrosative Stress and Inflammation in Mice. J Biochem Molecular Toxicology 2016. 30 (12): 571-579.

PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy; P Komirishetty, A Areti, VG Yerra, PK Ruby, SS Sharma, R Gogoi, R Sistla, A Kumar, Life sciences, 2016, 150, 50-60. 5.

Chemopreventive effect of chrysin, a dietary flavone against benzo (a) pyrene induced lung carcinogenesis in Swiss albino mice; Eshvendar Reddy Kasala, Lakshmi Narendra Bodduluru, Chandan C Barua, Rajaram Mohanrao Madhana, Vicky Dahiya, Mukesh Kumar Budhani, Ramana Reddy Mallugari, Suseela Reddy Maramreddy, Ranadeep Gogoi, Pharmacological Reports, 2016, 68 (2), 310-318.

Ghosh S.; Mohan U.; Banerjee U.C. “Studies on the production of shikimic acid using the aroK knockout strain of Bacillus megaterium”. World J. Microbiol. Biotechnol., 2016, 32(8):127.

Athira K.V., Rajaram Mohanrao Madhana, Mangala Lahkar; Flavonoids, the emerging dietary supplement against cisplatin-induced nephrotoxicity, Chemico-Biological Interactions, 2016, 248, 18–20.

Kunjbihari Sulakhiya, Gohil Pratik Keshavlal, Babul B. Bezbaruah, Shubham Dwivedi, Satendra Singh Gurjar, Nitin Munde, Ashok Jangra, Mangala Lahkar, Ranadeep Gogoi. Lipopolysaccharide induced anxiety- and depressive-like behaviour in mice are prevented by chronic pre-treatment of esculetin; Neuroscience Letters, 2016, 611, 106-111.

Ratan J. Lihite, Mangala Lahkar, Ajoy Borah, Debeeka Hazarika, Sukhjinder Singh. A study on drug induced Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN) and SJS-TEN overlap in a tertiary care hospital of Northeast India; J Young Pharm, 2016; 8(2): 146-150.

Ashok Jangra, Shubham Dwivedi, Chandra Shaker Sriram, Satendra Singh Gurjar, Mohit Kwatra, Kunjbihari Sulakhiya, Chandana C. Baruah, Mangala Lahkar; Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice. European Journal of Pharmacology, 770, 2016, Pages 25–32.

Mukesh Kumar, Vicky Dahiya, Shruti Mishra, Dinesh Sharma, Neha Mishra, Mangla Lahkar; Cardiovascular disease prevalence and drug utilization patterns at a tertiary care hospital in northeastern India. IJPPS, 2016, Vol 8, Issue 6, 2016.

Mukesh Kumar, Eshvendar Reddy Kasala, Lakshmi Narendra Bodduluru, Vicky Dahiya, Mangala Lahkar; Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation. Inflammation Research, 2016, 65, 8, 613–622.

Eshvendar Reddy Kasala, Lakshmi Narendra Bodduluru, Chandana C. Barua, Ranadeep Gogoi; Antioxidant and antitumor efficacy of Luteolin, a dietary flavone on benzo(a)pyrene-induced experimental lung carcinogenesis. Biomedicine & Pharmacotherapy, 2016, 82, 568–577.

Lakshmi Narendra Bodduluru, Eshvendar Reddy Kasala, Rajaram Mohanrao Madhana, Chandana C. Barua, Md Iftikar Hussain, Prakash Haloi, Probodh Borah; Naringenin ameliorates inflammation and cell proliferation in benzo(a)pyrene induced pulmonary carcinogenesis by modulating CYP1A1, NFκB and PCNA expression. International Immunopharmacology, 2016, 30, 102–110.

Sahabuddin Ahmed, Nitin Mundhe, Manash Borgohain, Liakat Chowdhury, Mohit Kwatra, Nityanand Bolshette, Anwaruddin Ahmed, Mangala Lahkar; Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy. Inflammation, 2016, 39(5):1783-1797.

Eshvendar Reddy Kasala, Lakshmi Narendra Bodduluru, Chandan C Barua, Rajaram Mohanrao Madhana, Vicky Dahiya, Mukesh Kumar Budhani, Ramana Reddy Mallugari, Suseela Reddy Maramreddy, Ranadeep Gogoi; Chemopreventive effect of chrysin, a dietary flavone against benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice, Pharmacol Rep 2016, 68(2), 310–318.

Vinayak Sudhir Jamdade, Nitin A. Mundhe, Parveen Kumar, Venkatesh Tadla, Mangala Lahkar; Raloxifene Inhibits NF-kB Pathway and Potentiates Anti-Tumour Activity of Cisplatin with Simultaneous Reduction in its Nephrotoxicity. 2016, Pathology & Oncology Research, 22(1), 145–153.

Chandra Shaker Sriram, Ashok Jangra, Satendra Singh Gurjar, Pritam Mohan, Babul Kumar Bezbaruah; Edaravone abrogates LPS-induced behavioral anomalies, neuroinflammation and PARP-1. 2016, Physiology & Behavior, 154, 135–144.

Ashok Jangra, Chandra Shaker Sriram, Mangala Lahkar; Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade. 2016, Inflammation, 39(4), 1441–1452.

Sukhjinder Singh, Ratan J. Lihite, Chitralekha Baruah, Mangala Lahkar, Prashant Kumar Singh; A pilot study of comorbidities in patients with Rheumatoid Arthritis at a tertiary care hospital in Northeast India, 2016, Biomed. Res. Ther. 2016; 3(1): 454-459.

Kundlik Gadhave, Nityanand Bolshette, Ashutosh Ahire, Rohit Pardeshi, Krishan Thakur, Cristiana Trandafir, Alexandru Istrate, Sahabuddin Ahmed, Mangala Lahkar, Dafin F. Muresanu, Maria Balea; J. Cell Mol. Med., 2016, 20(7), 1392-407.

Ratan J. Lihite, Mangala Lahkar, Sukirti Das, Debeeka Hazarika, Murali Kotnie, Mudasir Maqbool, Swapna Phukan; A study on adverse drug reactions in a tertiary care hospital of Northeast India, Alexandria Journal of Medicine 2017, 2 : 151-156.

Mukesh Kumar, Eshvendar Reddy Kasala, Lakshmi Narendra Bodduluru, Vicky Dahiya, Dinesh Sharma, Vikas Kumar, Mangala Lahkara; Animal models of myocardial infarction: Mainstay in clinical translation, Regulatory Toxicology and Pharmacology, 2016, 76, 221-230.

Ashok Jangra, Mohit Kwatra, Tavleen singh, Rajat Pant, Pawan Kushwah, Sahabuddin Ahmed, Durgesh Dwivedi, Babita Saroha, Mangala Lahkar; Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus, European Journal of Pharmacology, 2016, 15;791:51-61.

Ashok Jangra, Mohit Kwatra, Tavleen Singh, Rajat Pant, Pawan Kushwah, Yogita Sharma, Babita Saroha, Ashok Kumar Datusalia, Babul Kumar Bezbaruah; Piperine Augments the Protective Effect of Curcumin Against Lipopolysaccharide-Induced Neurobehavioral and Neurochemical Deficits in Mice, Inflammation, 2016, 39(3), 1025–1038.

Prashanth Komirishetty, Aparna Areti, Ranadeep Gogoi, Ramakrishna Sistla, Ashutosh Kumar, Poly (ADP-ribose) polymerase inhibition reveals a potential mechanism to promote neuroprotection and treat neuropathic pain; Neural Regeneration Research, 2016, 11(10):1545-1548.


2015

Pavan Kumar Samudrala, Bibin Baby Augustine, Eshvendar Reddy Kasala, Lakshmi Narendra Bodduluru, Chandana Barua, Mangala Lahkar. Evaluation of antitumor activity and antioxidant status of Alternanthera brasiliana against Ehrlich ascites carcinoma in Swiss albino mice. Pharmacognosy research 2015; 7(1): 66-73.

Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives; ER Kasala, LN Bodduluru, RM Madana, R Gogoi, CC Barua; Toxicology letters, 2015, 233 (2), 214-225.

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway; SR Kolati, ER Kasala, LN Bodduluru, JR Mahareddy, SK Uppulapu, Gogoi R, Barua CC, Lahkar M; Environmental toxicology and pharmacology, 2015, 39 (2), 690-699. 3.

Benzo (a) pyrene induced lung cancer: Role of dietary phytochemicals in chemoprevention; ER Kasala, LN Bodduluru, CC Barua, SC Shekhar, R Gogoi, Pharmacological Reports, 2015, 67(5), 996-1009.

"Resveratrol ameliorates depressive-like behavior in repeated corticosterone-induced depression in mice." Ali SH, Madhana RM, K V A, Kasala ER, Bodduluru LN, Pitta S, Mahareddy JR, Lahkar M. Steroids. 2015 Jun 3;101:37-42.

Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus. Jangra A, Kasbe P, Pandey SN, Dwivedi S, Gurjar SS, Kwatra M, Mishra M, Venu AK, Sulakhiya K, Gogoi R, Sarma N, Bezbaruah BK, Lahkar M. Biol. Trace Elem. Res. 2015 May 28.

Mangiferin ameliorates aluminium chloride-induced cogniti"e dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level. Kasbe P, Jangra A, Lahkar M. J. Trace Elem. Med. Biol. 2015 Jul;31:107-12.

Chrysin and its emerging role in cancer drug resistance; ER Kasala, LN Bodduluru, CC Barua, R Gogoi, Chemico-biological interactions,2015, 236, 7-8.

"Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice." Sriram CS, Jangra A, Gurjar SS, Hussain MI, Borah P, Lahkar M, Mohan P, Bezbaruah BK. Pharmacol Biochem Behav. 2015 Jun;133:83-91.

"Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases." Sriram CS, Jangra A, Madhana RM, Gurjar SS, Mohan P, Bezbaruah BK. Neural Regen Res. 2015 Jan;10(1):49-51.

"Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice." Sulakhiya K, Kumar P, Gurjar SS, Barua CC, Hazarika NK. Pharmacol Biochem Behav. 2015 Feb 26;132:79-87.

"Evaluation of antitumor activity and antioxidant status of Alternanthera brasiliana against Ehrlich ascites carcinoma in Swiss albino mice." Samudrala PK, Augustine BB, Kasala ER, Bodduluru LN, Barua C, Lahkar M. Pharmacognosy Res. 2015 Jan-Mar;7(1):66-73.

"Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives." Kasala ER, Bodduluru LN, Madana RM, V AK, Gogoi R, Barua CC. Toxicol Lett. 2015 Mar 4;233(2):214-25.

"Natural killer cells: the journey from puzzles in biology to treatment of cancer." Bodduluru LN, Kasala ER, Madhana RM, Sriram CS. Cancer Lett. 2015 Feb 28;357(2):454-67.

KK Thakur, NB Bolshette, C Trandafir, VS Jamdade, A Istrate, R Gogoi, Experimental Role of toll-like receptors in multiple myeloma and recent advances; hematology, 2015, 43 (3), 158-167.

Gogoi Ranadeep Yadav R. N. S. · Sharma S. K., Alteration Of Membrane Proteins In Red Blood Cells With Haemoglobin E (Hbe); Asian Academic Research Journal of Multidisciplinary, 2015, 2(4):323-330.


2014

Bibin Baby Augustine, Suvakanta Dash, Mangala Lahkar, Usha Sharma, Pavan Kumar Samudrala, Jaya Mary Thomas. Leucas aspera inhibits the Dalton’s ascitic lymphoma in Swiss albino mice: A preliminary study exploring possible mechanism of action. Pharmacognosy Magazine 2014; 10(38): 118-124.

Bibin Baby Augustine, Sathish Pitta, Mangala Lahkar, Suvakanta Dash, Pavan Kumar Samudrala, Jaya Mary Thomas. Ulcer protective effect of Leucas aspera in various experimental ulcer models. Asian Pacific Journal of Tropical Disease 2014; 4(Suppl 1): 395-402.

Bibin Baby Augustine, Suvakanta Dash, Mangala Lahkar, Venketeswara Rao Amara, Pavan Kumar Samudrala, Jaya Mary Thomas. Evaluation of immunomodulatory activity of ethyl acetate extract of Leucas aspera in Swiss albino mice. International journal of Green Pharmacy 2014. 8: 84-89.

"Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice." Sulakhiya K, Kumar P, Jangra A, Dwivedi S, Hazarika NK, Baruah CC, Lahkar M. Eur J Pharmacol. 2014 Dec 5;744:124-31.

"Effects of Cleome viscosa on hyperalgesia, oxidative stress and lipid profile in STZ induced diabetic neuropathy in Wistar rats." Rao BS, Reddy KE, Parveen K, Narendra BL, Shekhar SC, Mangala L. Pak J. Pharm. Sci. 2014 Sep;27(5):1137-45.

"Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice." Jangra A, Lukhi MM, Sulakhiya K, Baruah CC, Lahkar M. Eur J Pharmacol. 2014 Oct 5;740:337-45.

"Targeting poly(ADP-ribose)polymerase1 in neurological diseases: A promising trove for new pharmacological interventions to enter clinical translation." Sriram CS, Jangra A, Kasala ER, Bodduluru LN, Bezbaruah BK. Neurochem Int. 2014 Oct;76:70-81.

"Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms." Bodduluru LN, Kasala ER, Thota N, Barua CC, Sistla R. Toxicol In Vitro. 2014 Aug;28(5):1026-35.

"Protein folding and misfolding in the neurodegenerative disorders: a review". Bolshette NB, Thakur KK, Bidkar AP, Trandafir C, Kumar P, Gogoi R. Rev Neurol (Paris). 2014 Mar;170(3):151-61.

SV Prasanthi, VS Jamdade, NB Bolshette, R Gogoi, M Lahkar, Pharmacogenomics Study of Clopidogrel by RFLP based Genotyping of CYP2C19 in Cardiovascular Disease Patients in North-East Population of India; Journal of Pharmacogenomics & Pharmacoproteomics,2014, 5 (3):132.

Anil P Bidkar, Krishan K Thakur, Nityanand B Bolshette, Jyotibon Dutta and Ranadeep Gogoi, In-silico Structural and Functional Analysis of Hypothetical Proteins of Leptospira Interrogans; Biochem Pharmacol 2014, 3:3.


2013

Sanjeev Kumar Tiwari, Mangala Lahkar, Suvakanta Dash, Pavan Kumar Samudrala, Jaya Mary Thomas, Bibin Baby Augustine. Preliminary phytochemical, Toxicity and Anti-inflammatory Evaluation of Commelina benghalensis. International Journal of Green Pharmacy 2013; 7(3):201-205.

Bibin Baby Augustine, Suvakanta Dash, Mangala Lahkar, Ratan J Lihite, Pavan Kumar Samudrala, Sathish Pitta. Effect of Mirabilis jalapa linn flowers in experimentally induced arthritis and consecutive oxidative stress. International Journal of Pharmacy and Pharmaceutical Sciences 2013; 5(2):190-193.

Eshvendar Reddy Kasala, Bodduluru Lakshmi Narendra, Yogeshwar Maneti and Rajesh Thipparaboina. "Effect of meditation on neurophysiological changes in stress mediated depression." Complementary Therapies in Clinical Practice (2013).

Jay R. Anand, Harish Rijhwani, Kanakadurga Malapati, Parveen Kumar, Kandarpa Saikia, Mangala Lakhar. Anticancer activity of esculetin via-modulation of Bcl-2 and NF-?B expression in benzo[a]pyrene induced lung carcinogenesis in mice. Biomedicine & Preventive Nutrition; Volume 3, Issue 2, April–June 2013, Pages 107-112.

Parveen Kumar, Nityanand B. Bolshette, Vinayak S. Jamdade, Nitin A. Mundhe, Krishan K. Thakur, Kandrapa K. Saikia, Mangala Lahkar. Breast cancer status in India: An overview. Biomedicine & Preventive Nutrition; Volume 3, Issue 2, April–June 2013, Pages 177-183.

Parveen Kumar, Krishna Shastrula Prashanth, Anil Bhanudas Gaikwad, Mohit Vij, Chandana C. Barua, Babul Bezbaruah.Disparity in actions of rosiglitazone against cisplatin-induced nephrotoxicity in female Sprague-Dawley rats. Environmental Toxicology and Pharmacology, Volume 36, Issue 3, November 2013, Pages 883-890.

Parveen Kumar, Sonu Kumar, Chandana C. Barua. Breast cancer management. Biomed Pharmacol: 2013; In press corrected proof.

Boddapati Srinivasa Rao, Kasala Eshvendar Reddy, Kumar Parveen, Bodduluru Lakshmi Narendra, Sriram Chandra Shaker, Lahkar Mangala. Effects of Cleome viscosa on hyperalgesia, oxidative stress and lipid profile in STZ induced diabetic neuropathy in Wistar rats. Pakistan Journal of Pharmaceutical Sciences. 2013, Accepted Manuscript

Tiwari S, Lahkar M, Dash S, Samudrala PK, Thomas JM, Augustine BB. Preliminary phytochemical, Toxicity and Anti-inflammatory Evaluation of Commelina benghalensis. International Journal of Green Pharmacy 2013; 7(3).

Augustine BB, Dash S, Lahkar M, Sarma U, Samudrala PK, Thomas JM. Leucas aspera inhibits the Dalton’s ascitic lymphoma in Swiss albino mice: A preliminary study exploring possible mechanism of action. Pharmacognosy Magazine 2013.

Pitta S, Augustine BB, Reddy EJ, Sulakhiya KB, Killi R, Lahkar M. Honokiol reverses depressive-like behavior and decrease brain BDNF levels induced by chronic corticosterone injections in mice. Pharmacognosy Journal 2013.

Bibin Baby Augustine, Suvakanta Dash, Mangala Lahkar, Ratan J Lihite, Pavan Kumar Samudrala, Sathish Pitta. Effect of mirabilis jalapa flowers in experimentally induced arthritis and consecutive oxidative stress. International Journal of Pharmacy and Pharmaceutical Sciences; 2013, Volume 5, Issue 2, 190-193.

Bhaskarjyoti Dutta, Mangala Lahkar, Bibin Baby Augustine, Ratan J. Lihite. Hepatoprotective activity of tamarind indica and homalomena aromatica in rats. International Journal of Pharmacy and Pharmaceutical Sciences; 2013, Volume 5, Issue 2, 436-438.

Sriram Chandra Shaker, Lahkar Mangala, Kasala Eshvendar Reddy. Evaluation of anxiolytic activity of sesamol in swiss albino mice. American Journal of Pharmatech Research; 2013; 3 (2), 768-777.

AV Kiran Reddy, Ratan J. Lihite, Mangala Lahkar, Urmi Choudhury, Swaroop K. Baruah. A Study on Adverse Drug Reactions in HIV Infected Patients at a ART Centre of Tertiary Care Hospital in Guwahati, India Asian Journal of Pharmaceutical and Clinical Research. May 2013.

Usha Sarma, Jagadish Mahanta, Biswa J Borkakoty, Kunja L Talukdar, Ranadeep Gogoi, Kaushal Yadav, Demographic Characteristic Of Hpv Infection In Women - A Hospital Based Study From Guwahati, India; NATIONAL JOURNAL OF MEDICAL RESEARCH 2013, 3(1), 1-4.


2011-10

Sai Sampath T, Santosh P, Mangala Lahkar, Ajay Godwin P, Pavan Kumar S, Lingesh A. Antianxiety effect of Ethanolic extract of Oxalis corniculata in swiss albino mice. International journal of Pharma and Bio sciences 2011. 2: 281-290.,/p>

A Review on Cancer Vaccines, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- Vinodh Jaganti, Sukirti Das, T. Sai Sampath.

A Review on Ankylosing Spondylitis, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- V. Santhosh Kumar, Sukirti Das, T.Sai Sampath.

Role of Peroxynitrite in Diabetic Neuropathy: Peroxynitrite Decomposition Catalysts, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- Sampath Kumar.V, Lingesh.A, Bhaskar.B, Upender.A.

Anxiolytic Effect of Ethanolic Extract of Oxalis Corniculata .L in Mice, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- Sai Sampath. T, Santosh.P, Mangala Lahkar, Ajaygodwin.P, Pavan Kumar.S and Lingesh.A.

Review on Plant Derived Natural Products and Their Analogues with Chemo protective Activity against Genotoxicity of Cyclophosphamide, Ijpbs, Vol2, Issue3, Jul-Sept 201 -- Sai Sampath.T, Kanaka Durga. M, Saranya. BH, Kalyani.K.

Assessment of Drug Therapy in Geriatric Patients Using Beer’s Criteria, Journal of the Indian Academy of Geriatrics, Dec 2010 Issue, Vol 6, No: 4. -- Ratan J Lihite, Mangala Lahkar.

Antidepressant Activity of Methanolic Extract of Passifora foetida Leaves in Mice Santosh.P -- Dr.Mangala Lahkar, Venugopal.R, Nilakash As, Kunjbihari.S.