Research

Publications at NIPER Guwahati


2015

"Resveratrol ameliorates depressive-like behavior in repeated corticosterone-induced depression in mice." Ali SH, Madhana RM, K V A, Kasala ER, Bodduluru LN, Pitta S, Mahareddy JR, Lahkar M. Steroids. 2015 Jun 3;101:37-42.

Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus. Jangra A, Kasbe P, Pandey SN, Dwivedi S, Gurjar SS, Kwatra M, Mishra M, Venu AK, Sulakhiya K, Gogoi R, Sarma N, Bezbaruah BK, Lahkar M. Biol. Trace Elem. Res. 2015 May 28.

Mangiferin ameliorates aluminium chloride-induced cogniti"e dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level. Kasbe P, Jangra A, Lahkar M. J. Trace Elem. Med. Biol. 2015 Jul;31:107-12.

"Chrysin and its emerging role in cancer drug resistance.” Kasala ER, Bodduluru LN, Barua CC, Gogoi R. Chem. Biol. Interact. 2015 Jul 5;236:7-8.

"Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice." Sriram CS, Jangra A, Gurjar SS, Hussain MI, Borah P, Lahkar M, Mohan P, Bezbaruah BK. Pharmacol Biochem Behav. 2015 Jun;133:83-91.

"Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases." Sriram CS, Jangra A, Madhana RM, Gurjar SS, Mohan P, Bezbaruah BK. Neural Regen Res. 2015 Jan;10(1):49-51.

"Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice." Sulakhiya K, Kumar P, Gurjar SS, Barua CC, Hazarika NK. Pharmacol Biochem Behav. 2015 Feb 26;132:79-87.

"Evaluation of antitumor activity and antioxidant status of Alternanthera brasiliana against Ehrlich ascites carcinoma in Swiss albino mice." Samudrala PK, Augustine BB, Kasala ER, Bodduluru LN, Barua C, Lahkar M. Pharmacognosy Res. 2015 Jan-Mar;7(1):66-73.

"Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives." Kasala ER, Bodduluru LN, Madana RM, V AK, Gogoi R, Barua CC. Toxicol Lett. 2015 Mar 4;233(2):214-25.

"Natural killer cells: the journey from puzzles in biology to treatment of cancer." Bodduluru LN, Kasala ER, Madhana RM, Sriram CS. Cancer Lett. 2015 Feb 28;357(2):454-67.


2014

"Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice." Sulakhiya K, Kumar P, Jangra A, Dwivedi S, Hazarika NK, Baruah CC, Lahkar M. Eur J Pharmacol. 2014 Dec 5;744:124-31.

"Effects of Cleome viscosa on hyperalgesia, oxidative stress and lipid profile in STZ induced diabetic neuropathy in Wistar rats." Rao BS, Reddy KE, Parveen K, Narendra BL, Shekhar SC, Mangala L. Pak J. Pharm. Sci. 2014 Sep;27(5):1137-45.

"Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice." Jangra A, Lukhi MM, Sulakhiya K, Baruah CC, Lahkar M. Eur J Pharmacol. 2014 Oct 5;740:337-45.

"Targeting poly(ADP-ribose)polymerase1 in neurological diseases: A promising trove for new pharmacological interventions to enter clinical translation." Sriram CS, Jangra A, Kasala ER, Bodduluru LN, Bezbaruah BK. Neurochem Int. 2014 Oct;76:70-81.

"Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms." Bodduluru LN, Kasala ER, Thota N, Barua CC, Sistla R. Toxicol In Vitro. 2014 Aug;28(5):1026-35.

"Protein folding and misfolding in the neurodegenerative disorders: a review". Bolshette NB, Thakur KK, Bidkar AP, Trandafir C, Kumar P, Gogoi R. Rev Neurol (Paris). 2014 Mar;170(3):151-61.


2013

Eshvendar Reddy Kasala, Bodduluru Lakshmi Narendra, Yogeshwar Maneti and Rajesh Thipparaboina. "Effect of meditation on neurophysiological changes in stress mediated depression." Complementary Therapies in Clinical Practice (2013).

Jay R. Anand, Harish Rijhwani, Kanakadurga Malapati, Parveen Kumar, Kandarpa Saikia, Mangala Lakhar. Anticancer activity of esculetin via-modulation of Bcl-2 and NF-?B expression in benzo[a]pyrene induced lung carcinogenesis in mice. Biomedicine & Preventive Nutrition; Volume 3, Issue 2, April–June 2013, Pages 107-112.

Parveen Kumar, Nityanand B. Bolshette, Vinayak S. Jamdade, Nitin A. Mundhe, Krishan K. Thakur, Kandrapa K. Saikia, Mangala Lahkar. Breast cancer status in India: An overview. Biomedicine & Preventive Nutrition; Volume 3, Issue 2, April–June 2013, Pages 177-183.

Parveen Kumar, Krishna Shastrula Prashanth, Anil Bhanudas Gaikwad, Mohit Vij, Chandana C. Barua, Babul Bezbaruah.Disparity in actions of rosiglitazone against cisplatin-induced nephrotoxicity in female Sprague-Dawley rats. Environmental Toxicology and Pharmacology, Volume 36, Issue 3, November 2013, Pages 883-890.

Parveen Kumar, Sonu Kumar, Chandana C. Barua. Breast cancer management. Biomed Pharmacol: 2013; In press corrected proof.

Boddapati Srinivasa Rao, Kasala Eshvendar Reddy, Kumar Parveen, Bodduluru Lakshmi Narendra, Sriram Chandra Shaker, Lahkar Mangala. Effects of Cleome viscosa on hyperalgesia, oxidative stress and lipid profile in STZ induced diabetic neuropathy in Wistar rats. Pakistan Journal of Pharmaceutical Sciences. 2013, Accepted Manuscript

Tiwari S, Lahkar M, Dash S, Samudrala PK, Thomas JM, Augustine BB. Preliminary phytochemical, Toxicity and Anti-inflammatory Evaluation of Commelina benghalensis. International Journal of Green Pharmacy 2013; 7(3).

Augustine BB, Dash S, Lahkar M, Sarma U, Samudrala PK, Thomas JM. Leucas aspera inhibits the Dalton’s ascitic lymphoma in Swiss albino mice: A preliminary study exploring possible mechanism of action. Pharmacognosy Magazine 2013.

Pitta S, Augustine BB, Reddy EJ, Sulakhiya KB, Killi R, Lahkar M. Honokiol reverses depressive-like behavior and decrease brain BDNF levels induced by chronic corticosterone injections in mice. Pharmacognosy Journal 2013.

Bibin Baby Augustine, Suvakanta Dash, Mangala Lahkar, Ratan J Lihite, Pavan Kumar Samudrala, Sathish Pitta. Effect of mirabilis jalapa flowers in experimentally induced arthritis and consecutive oxidative stress. International Journal of Pharmacy and Pharmaceutical Sciences; 2013, Volume 5, Issue 2, 190-193.

Bhaskarjyoti Dutta, Mangala Lahkar, Bibin Baby Augustine, Ratan J. Lihite. Hepatoprotective activity of tamarind indica and homalomena aromatica in rats. International Journal of Pharmacy and Pharmaceutical Sciences; 2013, Volume 5, Issue 2, 436-438.

Sriram Chandra Shaker, Lahkar Mangala, Kasala Eshvendar Reddy. Evaluation of anxiolytic activity of sesamol in swiss albino mice. American Journal of Pharmatech Research; 2013; 3 (2), 768-777.

AV Kiran Reddy, Ratan J. Lihite, Mangala Lahkar, Urmi Choudhury, Swaroop K. Baruah. A Study on Adverse Drug Reactions in HIV Infected Patients at a ART Centre of Tertiary Care Hospital in Guwahati, India Asian Journal of Pharmaceutical and Clinical Research. May 2013.


2011-10

A Review on Cancer Vaccines, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- Vinodh Jaganti, Sukirti Das, T. Sai Sampath.

A Review on Ankylosing Spondylitis, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- V. Santhosh Kumar, Sukirti Das, T.Sai Sampath.

Role of Peroxynitrite in Diabetic Neuropathy: Peroxynitrite Decomposition Catalysts, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- Sampath Kumar.V, Lingesh.A, Bhaskar.B, Upender.A.

Anxiolytic Effect of Ethanolic Extract of Oxalis Corniculata .L in Mice, Ijpbs, Vol2, Issue3, Jul-Sept 2011 -- Sai Sampath. T, Santosh.P, Mangala Lahkar, Ajaygodwin.P, Pavan Kumar.S and Lingesh.A.

Review on Plant Derived Natural Products and Their Analogues with Chemo protective Activity against Genotoxicity of Cyclophosphamide, Ijpbs, Vol2, Issue3, Jul-Sept 201 -- Sai Sampath.T, Kanaka Durga. M, Saranya. BH, Kalyani.K.

Assessment of Drug Therapy in Geriatric Patients Using Beer’s Criteria, Journal of the Indian Academy of Geriatrics, Dec 2010 Issue, Vol 6, No: 4. -- Ratan J Lihite, Mangala Lahkar.

Antidepressant Activity of Methanolic Extract of Passifora foetida Leaves in Mice Santosh.P -- Dr.Mangala Lahkar, Venugopal.R, Nilakash As, Kunjbihari.S.